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To semantically enrich the laboratory data dictionary of the Study of Health in Pomerania (SHIP), a population-based cohort study, with LOINC to achieve better compliance with the FAIR principles for data stewardship.

Prediction of mortality in intensive care unit (ICU) patients typically relies on black box models (that are unacceptable for use in hospitals) or hand-tuned interpretable models (that might lead to the loss in performance). We aim to bridge the gap between these 2 categories by building on modern interpretable machine learning (ML) techniques to design interpretable mortality risk scores that are as accurate as black boxes.

To develop a distributed algorithm to fit multi-center Cox regression models with time-varying coefficients to facilitate privacy-preserving data integration across multiple health systems.

Diagnosis codes documented in electronic health records (EHR) are often relied upon to clinically phenotype patients for biomedical research. However, these diagnoses can be incomplete and inaccurate, leading to false negatives when searching for patients with phenotypes of interest. This study aims to determine whether PheMAP, a comprehensive knowledgebase integrating multiple clinical terminologies beyond diagnosis to capture phenotypes, can effectively identify patients lacking relevant EHR diagnosis codes.

Building upon our previous work on predicting chronic opioid use using electronic health records (EHR) and wearable data, this study leveraged the Health Equity Across the AI Lifecycle (HEAAL) framework to (a) fine tune the previously built model with genomic data and evaluate model performance in predicting chronic opioid use and (b) apply IBM's AIF360 pre-processing toolkit to mitigate bias related to gender and race and evaluate the model performance [...]

To develop a corpus annotated for diet-microbiome associations from the biomedical literature and train natural language processing (NLP) models to identify these associations, thereby improving the understanding of their role in health and disease, and supporting personalized nutrition strategies.

Heightened muscular effort and breathlessness (dyspnea) are disabling sensory experiences. We sought to improve the current approach of assessing these symptoms only at the maximal effort to new paradigms based on their continuous quantification throughout cardiopulmonary exercise testing (CPET).

Patient portals bridge patient and provider communications but exacerbate physician and nursing burnout. Large language models (LLMs) can generate message responses that are viewed favorably by healthcare professionals; however, these studies have not included diverse message types or new prompt-engineering strategies. Our goal is to investigate and compare the quality and precision GPT-generated message responses versus real doctor responses across the spectrum of message types within a patient portal.

Registered nurses increasingly work in remote care and digital interaction roles, offering flexibility and expansion of their scope of practice. These roles may expose nurses to digital compassion fatigue, a phenomenon proposed to be characterized by the negative psychological and emotional impact of caring for patients remotely through the use technology.

Introduction While computerized provider order entry (CPOE) has become standard for medication, laboratory, referral, and imaging ordering, use in surgical case requests is not well described. Our many surgical clinics used varying workflows for case requests, leading to data duplication and data storage outside of the electronic health record (EHR). We hypothesized that a provider-entered order-based case request (OBCR) tool would improve data entry efficiency and provide a more comprehensive [...]