In with the old, in with the new: machine learning for time to event biomedical research.
The predictive modeling literature for biomedical applications is dominated by biostatistical methods for survival analysis, and more recently some out of the box machine learning approaches. In this article, we show a presentation of a machine learning method appropriate for time-to-event modeling in the area of prostate cancer long-term disease progression. Using XGBoost adapted to long-term disease progression, we developed a predictive model for 118 788 patients with localized prostate cancer [...]
Author(s): Danciu, Ioana, Agasthya, Greeshma, Tate, Janet P, Chandra-Shekar, Mayanka, Goethert, Ian, Ovchinnikova, Olga S, McMahon, Benjamin H, Justice, Amy C
DOI: 10.1093/jamia/ocac106