Longitudinal clustering of Life's Essential 8 health metrics: application of a novel unsupervised learning method in the CARDIA study.
Changes in cardiovascular health (CVH) during the life course are associated with future cardiovascular disease (CVD). Longitudinal clustering analysis using subgraph augmented non-negative matrix factorization (SANMF) could create phenotypic risk profiles of clustered CVH metrics.
Author(s): Graffy, Peter, Zimmerman, Lindsay, Luo, Yuan, Yu, Jingzhi, Choi, Yuni, Zmora, Rachel, Lloyd-Jones, Donald, Allen, Norrina Bai
DOI: 10.1093/jamia/ocad240