Wasm-iCARE: a portable and privacy-preserving web module to build, validate, and apply absolute risk models.
Absolute risk models estimate an individual's future disease risk over a specified time interval. Applications utilizing server-side risk tooling, the R-based iCARE (R-iCARE), to build, validate, and apply absolute risk models, face limitations in portability and privacy due to their need for circulating user data in remote servers for operation. We overcome this by porting iCARE to the web platform.
Author(s): Balasubramanian, Jeya Balaji, Choudhury, Parichoy Pal, Mukhopadhyay, Srijon, Ahearn, Thomas, Chatterjee, Nilanjan, García-Closas, Montserrat, Almeida, Jonas S
DOI: 10.1093/jamiaopen/ooae055