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To examine the discrimination, calibration, and algorithmic fairness of the Epic End of Life Care Index (EOL-CI).

Common Data Elements (CDEs) standardize data collection and sharing across studies, enhancing data interoperability and improving research reproducibility. However, implementing CDEs presents challenges due to the broad range and variety of data elements. This study aims to develop a CDE mapping tool to bridge the gap between local data elements and National Institutes of Health (NIH) CDEs.

The US healthcare system faces significant challenges, including clinician burnout, operational inefficiencies, and concerns about patient safety. Artificial intelligence (AI), particularly generative AI, has the potential to address these challenges, but its adoption, effectiveness, and barriers to implementation are not well understood.

Primary graft dysfunction (PGD) is an essential outcome after the heart transplant, which causes severe complications and symptoms for recipients. The in advance prediction of PGD can help the transplant physician better manage the risks of PGD occurrence for patients. Domain experts have identified some important risk factors leading to PGD. However, a widely accepted PGD prediction method is lacking from a computational perspective. In this work, we focus on [...]

Despite the benefits of Clinical Decision Support (CDS), concerns of potential risks arise amidst increasing reports of CDS malfunctions. Without objective and standard methods to evaluate CDS in post-live stage, CDS performance in dynamic healthcare environment remains a black box from user perspective. In this study, we proposed a comprehensive framework to identify and evaluate post-live CDS malfunctions from the perspective of healthcare settings.

The integration of predictive models into live clinical care requires scientific testing before implementation to ensure patient safety. We built and technically implemented a model that predicts which patients require an electrocardiogram (ECG) to screen for heart attacks within 10 minutes of their arrival to the Emergency Department. We developed a structured framework for the in vitro to in vivo translation of the model through implementation as clinical decision support [...]

Telemedicine use has surged since the COVID-19 pandemic, offering a convenient way for patients to access healthcare. Whereas digital literacy (general comfort with and ability to use digital tools) is necessary to utilize telemedicine, digital health literacy is a subset of this, focusing on the ability to use digital tools to seek out, understand, and utilize health information. As such, barriers such as the lack of high-speed internet and limited [...]

This study aims to enhance the diagnostic process for rare diseases using case-based reasoning (CBR). CBR compares new cases with historical data, utilizing both structured and unstructured clinical data.

Despite its morbidity, mortality, and financial burden, in-hospital malnutrition remains underdiagnosed and undertreated. Artificial intelligence offers a promising clinical informatics solution for identifying malnutrition risk and one that can be coupled with clinician-delivered patient care.

Extracting social determinants of health (SDoHs) from medical notes depends heavily on labor-intensive annotations, which are typically task-specific, hampering reusability and limiting sharing. Here, we introduce SDoH-GPT, a novel framework leveraging few-shot learning large language models (LLMs) to automate the extraction of SDoH from unstructured text, aiming to improve both efficiency and generalizability.