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From a slate of candidate papers recommended by the Annual Symposium Scientific Program Committee, the Awards Committee will recognize up to five notable and distinguished papers from the Annual Symposium. Distinguished papers are awarded at Annual Symposium but contain no ordinal designation. Papers of the Student Paper Competition finalists are not eligible. Prior to 2004, AMIA provided awards for Best Paper Theoretical and Best Paper Applied.

Past Winners


Controversial Trials First: Identifying Disagreement Between Clinical Guidelines and New Evidence

  • Florian Borchert, Digital Health Center, Hasso Platter Institute, University of Potsdam, Germany
  • Laura Meister, Digital Health Center, Hasso Platter Institute, University of Potsdam, Germany
  • Thomas Langer, Dipl. Social Scientist, German Guideline Program in Oncology, German Cancer Society, Berlin, Germany
  • Markus Follmann, MD, MPH, MSc, German Guideline Program in Oncology, German Cancer Society, Berlin, Germany
  • Bert Arnrich, PhD, Digital Health Center, Hasso Platter Institute, University of Potsdam, Germany
  • Matthieu-P. Schapranow, PhD, Digital Health Center, Hasso Platter Institute, University of Potsdam, Germany

Creation of a Mapped, Machine-Readable Taxonomy to Facilitate Extraction of Social Determinants of Health Data from Electronic Health Records

  • Svati B. Patel, MHS MSc, Veradigm, Chicago, IL
  • Nam T. Nguyen, MS, Veradigm, San Francisco, CA

A Comparison of Exhaustive and Non-lattice-based Methods for Auditing; Hierarchical Relations in Gene Ontology

  • Rashmie Abeysinghe, PhD, Department of Neurology, University of Texas Health Science Center at Houston, Houston, TX
  • Fengbo Zheng, PhD, School of Biomedical Informatics, University of Texas Health Science Center at Houston Houston, TX
  • Licong Cui, PhD, School of Biomedical Informatics, University of Texas Health Science Center at Houston Houston, TX


  • Is Deep Reinforcement Learning Ready for Practical Applications in Healthcare? A Sensitivity Analysis of Duel-DDQN for Hemodynamic Management in Sepsis Patients
    MingYu Lu, MIT; Zachary Shahn, Daby Sow, IBM Research; Finale Doshi-Valez, Harvard University; Li-wei Lehman, MIT
  • Privacy-preserving Methods for Vertically Partitioned Incomplete Data
    Yi Deng, Emory University; Xiaoqian Jian, University of Texas Health Science Center at Houston; Qi Long, University of Pennsylvania
  • Improving the Utility of Tobacco-related Problem List Entries Using Natural Language Processing
    Daniel Harris, Institute of Pharmaceutical Outcomes and Policy, College of Pharmacy, Center for Clinical and Translational Services, University of Kentucky; Darren Henderson, Alexandria Corbeau, Center for Clinical and Translational Services, University of Kentucky
  • Evaluating the Coverage of the HL7® FHIR® Standard to Support eSource Data Exchange Implementations for Use in Multi-Site Clinical Research Studies
    Maryam Garza, University of Arkansas for Medical Sciences, University of Texas Health Science Center at Houston; Michael Rutherford, University of Arkansas for Medical Sciences; Sahiti Myneni, Susan Fenton, University of Texas Health Science Center at Houston; Anita Walden, Oregon Health & Science University; Umit Topaloglu, Wake Forest University School of Medicine; Eric Eisenstein, Karan Kumar, Kanecia Zimmerman, Duke Clinical Research Institute; Mitra Rocca, Gideon Gordon, US Food & Drug Administration; Sam Hume, Clinical Data Interchange Standards Consortium; Zhan Wang, Meredith Zozus, University of Texas Health Science Center at San Antonio
  • Using Natural Language Processing and Machine Learning to Identify Hospitalized Patients with Opioid User Disorder
    Suzanne Blackley, Mass General Brigham; Erin MacPaul, Division of General Medicine and Primary Care, Brigham and Women’s Hospital; Bianca Martin, Department of Psychiatry, Brigham and Women’s Hospital; Wenyu Song, Division of General Medicine and Primary Care, Brigham and Women’s Hospital, Harvard Medical School; Joji Suzuki, Department of Psychiatry, Brigham and Women’s Hospital; Li Zhou, Harvard Medical School


  • Biomedical Research Cohort Membership Disclosure on Social Media
    Yongtai Liu, Chao Yan, Zhijun Yin, Zhiyu Wan, Weiyi Xia, Vanderbilt University; Murat Kantarcioglu, The University of Texas at Dallas; Yevgeniy Vorobeychik, Washington University in St. Louis; Ellen W. Clayton, Bradley Malin, Vanderbilt University
  • Comparing Deep Learning Models for Multi-cell Classification in Liquid-based Cervical Cytology Images
    Sudhir Sornapudi, Missouri University of Science and Technology; Gregory T. Brown, Zhiyun Xue, Rodney Long, National Library of Medicine; Lisa Allen, Beston Dickinson and Company; Sameer Antani, National Library of Medicine
  • Bootstrapping Adversarial Learning of Biomedical Ontology Alignments
    Ramon Maldonado, Sanda M. Harabagiu, The University of Texas at Dallas


  • Interoperability Progress and Remaining Data Quality Barriers of Certified Health Information Technologies
    J. D'Amore, Diameter Health, Inc., Boston University; O. Bouhaddou, S. Mitchell, US Department of Veteran Affairs; C. Li, Diameter Health, Inc.; R. Leftwich, InterSystems, Inc.; T. Turner, US Department of Veteran Affairs, M. Rahn, Office of the National Coordinator for Health Information Technology; M. Donahue, J. Nebeker, US Department of Veteran Affairs
  • Learning to Personalize from Practice: A Real World Evidence Approach of Care Plan Personalization Based on Differential Patient Behavioral Responses in Care Management Records
    P.Y. Hsueh, S. Das, C. Maduri, IBM Research; K. Kelly, IBM Watson Health
  • Disease Trajectories and End-of-Life Care for Dementias: Latent Topic Modeling and Trend Analysis Using Clinical Notes
    L. Wang, Brigham and Women’s Hospital, Harvard Medical School; J. Lakin, Brigham and Women’s Hospital, Harvard Medical School, Dana-Farber Cancer Institute; C. Riley, Z. Korach, L. Frain, L. Zhou, Brigham and Women’s Hospital, Harvard Medical School


  • Mechanism-based Pharmacovigilance over the Life Sciences Linked Open Data Cloud
    Maulik R. Kamdar and Mark A. Musen, Stanford University
  • Comparing and Contrasting A Priori and A Posteriori Generalizability Assessment of Clinical Trials on Type 2 Diabetes Mellitus
    Zhe He, Arturo Gonzalez-Izquierdo, Spiros Denaxas, Andrei Sura, Yi Guo, William R. Hogan, Elizabeth Shenkman, Jiang Bian, Florida State University, University College London, University of Florida
  • Predicting Inpatient Acute Kidney Injury over Different Time Horizons: How Early and Accurate?
    Peng Cheng, Lemuel R. Waitman, Yong Hu, Mei Liu, University of Kansas Medical Center, Jinan University, Southwest University (China)


  • Combining Open-domain and Biomedical Knowledge for Topic Recognition in Consumer Health Questions
    Yassine Mrabet, Halil Kilicoglu, Kirk Roberts, Dina Demner-Fushman
  • Can Patient Record Summarization Support Quality Metric Abstraction?
    Rimma Pivovarov, Yael J. Coppleson, Sharon Lipsky Gorman, David Vawdrey, Noemie Elhadad
  • Identification and Use of Frailty Indicators from Text to Examine Associations with Clinical Outcomes Among Patients with Heart Failure
    Yijun Shao, April F. Mohanty, Ali Ahmed, Charlene Weir, Bruce E. Bray, Rashmee Shah, Douglas Redd, Qing Zeng-Treitler


  • Implementation and Evaluation of a Tele-education System for the Diagnosis of Ophthalmic Disease by International Trainees
    J. Campbell, R. Swan, Oregon Health & Science University; K. Jonas, Weill Cornell Medical College; S. Ostmo, Oregon Health & Science University; C. Ventura, 4Altino Ventura Foundation; M. Martinez-Castellanos, Asociacion para Evitar la Ceguera en México/Hospital Luis Sánchez Bulnes; R. Anzures, Ospital ng Makati; M. Chiang, Oregon Health & Science University; R. Chan, Weill Cornell Medical College
  • Simulation-based Evaluation of the Generalizability Index for Study Traits
    Z. He, P. Chandar, Columbia University; P. Ryan, Columbia University/Janssen Research and Development; C. Weng, Columbia University
  • Mortality Prediction in ICUs Using A Novel Time-slicing Cox Regression Method
    Y. Wang, W. Chen, K. Heard, M. Kollef, T. Bailey, Z. Cui, Y. He, C. Lu, Y. Chen, Washington University in St. Louis
  • Handling Temporality of Clinical Events for Drug Safety Surveillance
    J. Zhao, A. Henriksson, Stockholm University; M. Kvist, Stockholm University/Karolinska Institute; L. Asker, H. Boström, Stockholm University


  • Evaluating Health Interest Profiles Extracted from Patient-generated Data
    A. Hartzler, D. McDonald, A. Park, University of Washington; J. Huh, Michigan State University;C. Weaver, OMNI Health Media; W. Pratt, University of Washington
  • Development and Validation of an Electronic Phenotyping Algorithm for Chronic Kidney Disease
    G. Nadkarni; O. Gottesman, Icahn School of Medicine at Mount Sinai; J. Linneman, Marshfield Clinic Research Foundation; H. Chase, Columbia University Medical Center; R. Berg, Marshfield Clinic Research Foundation; S. Farouk, R. Nadukuru, V. Lotay, S. Ellis, Icahn School of Medicine at Mount Sinai; G. Hripcsak, Columbia University Medical Center/Icahn School of Medicine at Mount Sinai; P. Peissig, Marshfield Clinic Research Foundation; C. Weng, Columbia University Medical Center; E. Bottinger, Icahn School Of Medicine at Mount Sinai
  • Mining Consumer Health Vocabulary from Community-generated Text
    V. Vydiswaran, Q. Mei, D. Hanauer, K. Zheng, University of Michigan


  • Identifying Inconsistencies in SNOMED CT Problem Lists using Structural Indicators
    A. Agrawal, Manhattan College; Y. Perl, New Jersey Institute of Technology; Y. Chen, Borough of Manhattan Community College; G. Elhanan, Halfpenny Technologies; M. Liu, New Jersey Institute of Technology
  • On-time Clinical Phenotype Prediction Based on Narrative Reports
    C. Bejan, Vanderbilt University; L. Vanderwende, Microsoft; H. Evans, M. Wurfel, University of Wasington; M. Yetisgen-Yildiz, University of Washington
  • Patient Moderator Interaction in Online Health Communities
    J. Huh, D. McDonald, A. Hartzler, W. Pratt, University of Washington
  • Using Image References in Radiology Reports to Support Enhanced Report-to-Image Navigation
    T. Mabotuwana, Y. Qian, M. Sevenster, Philips Research North America
  • Twinlist: Novel User Interface Designs for Medication Reconciliation
    C. Plaisant, T. Chao, J. Wu, University of Maryland; A. Hettinger, Medstar Innovation Institute; J. Herskovic, The University of Texas Health Science Center at Houston/MD Anderson Cancer Center; T. Johnson, University of Kentucky; E. Bernstam, E. Markowitz, The University of Texas Health Science Center at Houston; S. Powsner, Yale University; B. Shneiderman, University of Maryland


  • Ensuring Patient Safety in Care Transitions: An Empirical Evaluation of a Handoff Intervention Tool
    Joanna Abraham, Thomas Kannampallil, Vimla Patel, New York Academy of Medicine; Bela Patel, Khalid Almoosa, University of Texas Houston Health Science Center
  • Exceptions Handling within GLARE Clinical Guideline Framework
    Giorgio Leonardi; Alessio Bottrighi; Gabriele Galliani; Paolo Terenziani; Antonio Messina; Francesco Della Corte, University of Pavia; University of Eastern Piedmont
  • Ontology-Based Federated Data Access to Human Studies Information
    Ida Sim, Simona Carini,University of California San Francisco; Samson W. Tu, Stanford University; Landon T. Detwiler, James Brinkley, University of Washington; Shamim A. Mollah, Knut M. Wittkowski, The Rockefeller University; Karl Burke, Harold P. Lehmann, Johns Hopkins University; Swati Chakraborty, Duke University; Brad H. Pollock, University of Texas Health Science Center; Thomas M. Johnson, Mayo Clinic; Vojtech Huser, National Institutes of Health
  • An Evaluation of the NQF Quality Data Model for Representing Electronic Health Record Driven Phenotyping Algorithms
    William K. Thompson, Luke V. Rasmussen, Jennifer A. Pacheco, Abel N. Kho, Northwestern University; Peggy L. Peissig, Aaron Miller, Marshfield Clinic; Joshua C. Denny, Vanderbilt University; Jyotishman Pathak, Mayo Clinic
  • The Orderly and Effective Visit: Impact of the Electronic Health Record on Modes of Cognitive Control
    Charlene Weir 1,2,4 ; Frank A Drews 2,5; Molly K Leecaster 2,3; Robyn J Barrus 2; James L Hellewell 2,4; Jonathan R Nebeker 1,2,3
    1. Department of Veterans Affairs, Geriatrics Research and Clinical Setting; 2. Informatics Decision Enhancement and Surveillance Research Center, VA, SLC, 3. Department of Internal Medicine, University of Utah; 4. Department of Bio-Medical Informatics, University of Utah; 5.Department of Psychology, University of Utah


  • A Multi-site Content Analysis of Social History Information in Clinical Notes
    Elizabeth Chen, I. Sarkar, University of Vermont; S. Manaktala, G. Melton, University of Minnesota
  • All Health Care is Not Local: an Evaluation of the Distribution of Emergency- Department Care Delivered in Indiana
    J.T. Finnell, M. Overhage, S. Grannis, Regenstrief Institute & Indiana University
  • Complex Disease Networks of Trait-associated SNPs Unveiled by Information Theory
    Haiquan Li, Y. Lee, J. Li, J. Chen, E. Rebman, K. Regan, Y. Lussier, University of Chicago
  • Lexically Suggest, Logically Define: Quality Assurance of the Use of Qualifiers and Expected Results of Post-Coordination in SNOMED CT
    Alan Rector, L. Iannone, University of Manchester
  • A Vector Space Model-based Approach to Identify Genetically Similar Diseases
    Indra Neil Sarkar, University of Vermont


  • Natural Language Processing for Lines and Devices in Portable Chest X-Rays
    D. Rubin, VA Palo Alto Health Care System and Stanford University; D. Wang, D. Chambers, J. Chambers, VA Palo Alto Health Care System; B. South, VA Salt Lake City Health Care System; M. Goldstein, VA Palo Alto Health Care System and Stanford University
  • I am Not Dead Yet: Identification of False-Positive Matches to Death Master File
    A. Turchin, Partners HealthCare; M. Shubina, Brigham and Women’s Hospital; S. Murphy, Massachusetts General Hospital
  • Impact of Electronic Medication Reconciliation at Hospital Admission on Clinician Workflow
    D. Vawdrey, N. Chang, Columbia University; A. Compton, V. Tiase, New York Presbyterian Hospital; G. Hripcsak, Columbia University
  • Large-scale, Exhaustive Lattice-based Structural Auditing of SNOMED CT
    G. Zhang, Case Western


  • Development and Evaluation of a Study Design Typology for Human Research
    Simona Carini, University of California, San Francisco
  • Development of a Natural Language Processing System to Identify Timing and Status of Colonoscopy Testing in Electronic Medical Records
    Joshua C. Denny, Vanderbilt University
  • Persistent Paper: The Myth of “Going Paperless
    Richard H. Dykstra, Oregon Health & Science University
  • Do Clinical Profiles Constitute Privacy Risks for Research Participants?
    Grigorios Loukides, Vanderbilt University
  • Serving the Enterprise and Beyond with Informatics for Integrating Biology and the Bedside (i2b2)
    Shawn N. Murphy, Massachusetts General Hospital
  • An Unintended Consequence of Electronic Prescriptions: Prevalence and Impact of Internal Discrepancies
    Matvey B. Palchuk, Harvard Medical School and Partners HealthCare System, Inc.


  • Optimizing Feature Representation for Automated Systematic Review Work Prioritization, Aaron Cohen, Oregon Health & Science University
  • The CHICA Smoking Cessation System, Stephen Downs, Vivienne Zhu, Vibha Anand, Paul Biondich, Aaron Carroll, Indiana University, Regenstrief Institute, Indianapolis, IN
  • Web Screening of U.S. Nursing Homes by Location and Quality, Glenn Pearson, Michael Gill, George Thoma, National Library of Medicine, Bethesda, MD
  • A Rapid Assessment Process for Clinical Informatics Interventions, Joan Ash, Dean Sittig, Carmit McMullen, Kenneth Guappone, Richard Dykstra, James Carpenter, Oregon Health & Science University, Kaiser Permanente Northwest, Providence Portland Medical Center
  • Extracting Structured Medication Event Information from Discharge Summaries, Sigfried Gold, Noémie Elhadad, Xinxin Zhu, James Cimino, George Hripcsak, Columbia University


  • Using the Literature-based Discovery Paradigm to Investigate Drug Mechanisms, C. Ahlers, H. Kilicoglu, D. Hristovski, T. Rindflesch
  • Network Analysis of Toxic Chemicals and Symptoms: Implications for Designing First-responder Systems, S. Bhavnani, A. Abraham, C. Demeniuk, R. Richardson, G. Valabha
  • A Rationale for Parsimonious Laboratory Term Mapping by Frequency, D. Vreeman, J. Finnell, J. Overhage


  • Infodemiology: Tracking Flu-Related Searches on the Web for Syndromic Surveillance, Gunther Eysenbach, University of Toronto & University Health Network, Toronto, Quebec, Canada
  • A Novel Method for the Efficient Retrieval of Similar Multiparameter Physiologic Time Series Using Wavelet-Based Symbolic Representations, Mohammed Saeed, Philips Medical Systems, Harvard-MIT, Cambridge, MA
  • Improving the Sensitivity of the Problem List in an Intensive Care Unit by Using Natural Language Processing, Stephane Meystre, University Hospital of Lausanne, Lausanne, Switzerland
  • Ontology-Based Representation of Stimulation Models of Physiology, Daniel Rubin, Stanford University, Palo Alto, CA
  • Barriers to Electronic Health Record Use during Patient Visits, Jeffrey Linder, Brigham and Women's Hospital, Boston, MA


  • Data Quality in the Outpatient Setting: Impact on Clinical Decision Support Systems, Eta S. Berner, Ramkumar K. Kasiraman, Feliciano Yu, Midge N. Ray, University of Alabama at Birmingham, Birmingham, AL; and Thomas K. Houston, University of Alabama at Birmingham and Birmingham VA Medical Center, Birmingham, AL
  • Deriving the Expected Utility of a Predictive Model When the Utilities are Uncertain, Gregory F. Cooper, and Shyam Visweswaran, University of Pittsburgh, Pittsburgh, PA
  • Two Dl-based Methods for Auditing Medical Terminological Systems, Ronald Cornet, Academic Medical Center, Dept of Medical Informatics, Amsterdam, Netherlands; and Ameen Abu-Hanna, Academic Medical Centre, Dept. of Medical Informatics, Amsterdam, Netherlands
  • Early Detection of Rotavirus Gastrointestinal Illness Outbreaks by Multiple Data Sources and Detection Algorithms at a Pediatric Health System, James E. Levin, Children’s Hospitals and Clinics, Saint Paul, MN; and Sivakumaran Raman, Children’s Hospitals and Clinics of Minnesota, Roseville, MN
  • Mapping Cancer Patients’ Symptoms to UMLS Concepts, Laura A. Slaughter, Cornelia M. Ruland, and AnnKristin Rotegård, Center for Shared Decision Making and Nursing Research, Oslo, Norway
  • Ontodiagram: Automatic Diagram Generation for Congenital Heart Defects in Pediatric Cardiology, Katik Vishwanath, Venkatesh Viswanath, University of Missouri - Kansas City, Kansas City, MO; William Drake, Section of Cardiology, The Children’s Mercy Hospitals and Clinics, Kansas City, MO; and Yugyung Lee, University of Missouri - Kansas City, Kansas City, MO


  • Classifying Instantaneous Cognitive States from fMRI Data, Tom M. Mitchell, R. Hutchinson, M.A. Just, R. S. Niculescu, F. Pereira, and X. Wang, Carnegie Mellon University, Pittsburgh, PA
  • A Cognitive Framework for Understanding Barriers to the Productive Use of a Diabetes Home Telemedicine System, David R. Kaufman, J. Starren, and V.L. Patel, Columbia University, New York, NY, P.C. Morin, SUNY Upstate Medical University, Syracuse, NY, C. Hillman, and J. Pevzner, Columbia University, New York, NY, R.S. Weinstock, SUNY Upstate Medical University, Syracuse, NY, R. Goland and S. Shea, Columbia University, New York, NY.


  • Exploring the Boundaries of Plausibility: Empirical Study of a Key Problem in the Design of Computer-based Clinical Simulations, Charles P. Friedman, PhD, G.G. Gatti, University of Pittsburgh, Pittsburgh, PA, G.C. Murphy, PhD, Duke University, Durham, NC, T.M. Franz, PhD, St. John Fisher College, Rochester, NY, P.L. Fine, MD, University of Michigan, Ann Arbor, MI, P.S. Heckerling, MD, University of North Carolina, Chapel Hill, NC
  • The Sublanguage of Cross-coverage, Peter D. Stetson, MD, S.B. Johnson, PhD, M. Scotch, G. Hripcsak, MD, MS, Department of Medical Informatics, Columbia University, New York, NY, USA


  • A Virtual Medical Record for Guideline-based Decision Support, Peter D. Johnson, MBBS
  • Development of Visual Diagnostic Expertise in Pathology, Rebecca S. Crowley, MD


  • Boosting Naïve Bayesian Learning on a Large Subset of MEDLINE, W. Wilbur, MD, PhD, National Library of Medicine, Bethesda, MD
  • ActiveGuidelines: Integrating Web-based Guidelines with Computer-based Patient Records, P.C. Tang, MD, and C.Y. Young, PhD, Epic Research Institute, Mountain View, CA.


  • Title. Nuala Beennett, MS, Graduate School of Library and Information Science, University of Illinois at Urbana
  • Title, Nick S. Booth, MD, University of Newcastle and Primary Healthcare Development Center, Newcastle General Hospital, Newcastle upon Tyne, UK


  • An Evaluation of Natural Language Processing Methodologies, Carol Friedman, George Hripcsak, and Irina Shablinsky, Columbia University
  • Improving Patient Outcomes by Including Patient Preferences in Nursing Care, Cornelia M. Ruland, PhD, RN


  • An Architecture for a Distributed Guideline Server, M. Barnes, MD, and G.O. Barnett, MD, Laboratory of Computer Science, Massachusetts General Hospital, Boston, Massachusetts
  • Creating Temporal Abstractions in Three Clinical Information Systems, M.G. Kahn, MD, PhD, and K.A. Marrs, MS, Section of Medical Informatics, Washington University, St. Louis, Missouri.


  • Development and Evaluation of a Computer-Assisted Management Protocol (CAMP): Improved Compliance with Care Guidelines for Diabetes Mellitus, D.P. Lobach, MD, PhD, MS, and W. E. Hammond, PhD, Division of Medical Informatics, Department of Biomedical Engineering and Department of Community and Family Medicine, Duke University, Durham, NC
  • The Use and Impact of a Computer-based Support System for People Living with AIDS and HIV Infection, David H. Gustafson, PhD
  • An Application of Expert Network to Clinical Classification and MEDLINE Indexing, Y. Yang, PhD, C.G. Chute, PhD, Section of Medical Information Resources, Mayo Clinic/Foundation, Rochester, MN


  • Words or Concepts: the Features of Indexing Units and their Optimal Use in Information Retrieval, Y. Yang, PhD, and C.G. Chute, PhD, Mayo Clinic/Foundation, Rochester, MN
  • Clinical Performance of a Rule-Based Decision Support System for Mechanical Ventilation of ARDS Patients, G.E. Thomsen, PhD, D. Pope, T.D. East, A.H. Morris, A.T. Kinder, D.A. Carlson, G.L. Smith, C.J. Wallace, J.F. Orme, Jr., T.P. Clemmer, L.K. Weaver, F. Thomas, and N.C. Dean, Pulmonary Divisions of the Departments of Internal Medicine, LDS Hospital and University of Utah, Salt Lake City, UT.