Appl Clin Inform 2023; 14(01): 65-75
DOI: 10.1055/a-1990-3037
Research Article

SEPRES: Intensive Care Unit Clinical Data Integration System to Predict Sepsis

Qiyu Chen
1   Division of Applied Mathematics, Fudan University, Shanghai, China
,
Ranran Li
2   Department of Critical Care Medicine, Shanghai Jiaotong University School of Medicine, Ruijin Hospital, Shanghai, China
,
ChihChe Lin
3   Department of Intelligent Medical Products, Shanghai Electric Group Co., Ltd. Central Academe, Shanghai, China
,
Chiming Lai
3   Department of Intelligent Medical Products, Shanghai Electric Group Co., Ltd. Central Academe, Shanghai, China
,
Yaling Huang
3   Department of Intelligent Medical Products, Shanghai Electric Group Co., Ltd. Central Academe, Shanghai, China
,
Wenlian Lu
1   Division of Applied Mathematics, Fudan University, Shanghai, China
,
Lei Li
2   Department of Critical Care Medicine, Shanghai Jiaotong University School of Medicine, Ruijin Hospital, Shanghai, China
› Author Affiliations

Abstract

Background The lack of information interoperability between different devices and systems in the intensive care unit (ICU) hinders further utilization of data, especially for early warning of specific diseases in the ICU.

Objectives We aimed to establish a data integration system. Based on this system, the sepsis prediction module was added to compose the Sepsis PREdiction System (SEPRES), where real-time early warning of sepsis can be implemented at the bedside in the ICU.

Methods Data are collected from bedside devices through the integration hub and uploaded to the integration system through the local area network. The data integration system was designed to integrate vital signs data, laboratory data, ventilator data, demographic data, pharmacy data, nursing data, etc. from multiple medical devices and systems. It integrates, standardizes, and stores information, making the real-time inference of the early warning module possible. The built-in sepsis early warning module can detect the onset of sepsis within 5 hours preceding at most.

Results Our data integration system has already been deployed in Ruijin Hospital, confirming the feasibility of our system.

Conclusion We highlight that SEPRES has the potential to improve ICU management by helping medical practitioners identify at-sepsis-risk patients and prepare for timely diagnosis and intervention.

Human Subjects Protections

The study was performed in compliance with the World Medical Association Declaration of Helsinki on Ethical Principles for Medical Research Involving Human Subjects, and was approved by the Ruijin Hospital Ethics Committee (no.: 2020 [140]).


Supplementary Material



Publication History

Received: 20 July 2022

Accepted: 28 November 2022

Accepted Manuscript online:
30 November 2022

Article published online:
25 January 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
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