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DOI: 10.1055/s-0038-1669457
Numeracy and Understanding of Quantitative Aspects of Predictive Models: A Pilot Study
Funding This work was supported by the National Institutes of Health/NHLBI (T32-HL098054), the Masters of Science in Health Policy Research Program, and the Center for Health Incentives and Behavioral Economics/Penn Roybal Center at the Leonard Davis Institute through a grant from the National Institutes of Health/NIA (P30-AG034546) at the Perelman School of Medicine, University of Pennsylvania. The views expressed here are those of the authors and not of the funders.Publication History
10 May 2018
17 July 2018
Publication Date:
29 August 2018 (online)


Abstract
Background The assessment of user preferences for performance characteristics of patient-oriented clinical prediction models is lacking. It is unknown if complex statistical aspects of prediction models are readily understandable by a general audience.
Objective A pilot study was conducted among nonclinical audiences to determine the feasibility of interpreting statistical concepts that describe the performance of prediction models.
Methods We conducted a cross-sectional electronic survey using the Amazon Mechanical Turk platform. The survey instrument included educational modules about predictive models, sensitivity, specificity, and confidence intervals (CIs). Follow-up questions tested participants' abilities to interpret these characteristics with both verbatim and gist knowledge. Objective and subjective numeracy were assessed using previously validated instruments. We also tested understanding of these concepts when embedded in a sample discrete choice experiment task to establish feasibility for future elicitation of preferences using a discrete choice experiment design. Multivariable linear regression was used to identify factors associated with correct interpretation of statistical concepts.
Results Among 534 respondents who answered all nine questions, the mean correct responses was 95.9% (95% CI, 93.8–97.4) for sensitivity, 93.1% (95% CI, 90.5–95.0) for specificity, and 86.6% (95% CI, 83.3–89.3) for CIs. Verbatim interpretation was high for all concepts, but significantly higher than gist only for CIs (p < 0.001). Scores on each discrete choice experiment tasks were slightly lower in each category. Both objective and subjective numeracy were positively associated with an increased proportion of correct responses (p < 0.001).
Conclusion These results suggest that a nonclinical audience can interpret quantitative performance measures of predictive models with very high accuracy. Future development of patient-facing clinical prediction models can feasibly incorporate patient preferences for model features into their development.
Keywords
forecasting - health communication - decision support techniques - clinical decision-making - education of patientsProtection of Human and Animal Subjects
This study was considered exempt by the Institutional Review Board of the University of Pennsylvania.